Platform Technology

GPCR heteromer database

  • Among a library of Ad-BiFC heteromer finders, 144 GPCRs tagged with Venus C-terminus and 126 GPCRs tagged with Venus N-terminus were used to test protein-protein interactions.
  • Among those 18,144 interactions (144 x 126) between Ad-BiFC heteromer finders, we identified 1,297 potential heteromers.
  • This GPCR heteromer database can be used to initiate new drug development programs targeting GPCRs.