GPCR heteromers are complexes formed through the association of distinct GPCRs.

These interactions can give rise to signaling profiles and functional properties that differ from those of the individual receptors.

Understanding how GPCR heteromers form—and how these interactions reshape receptor function—remains a key challenge in GPCR research.

By integrating the experimental capabilities and expertise built into GPS™, we investigate receptor–receptor interactions and characterize heteromer-specific properties from multiple perspectives.

These insights help us explore new opportunities for therapeutic discovery targeting GPCR heteromers.