Product

CXCR4

  • Gαi-protein coupled receptor that binds to CXCL12

  • CXCR4 is overexpressed in more than 23 different cancer types

  • Plays pivotal role in cancer progression by regulating tumor growth, metastasis, angiogenesis, and therapeutic resistance
  • In patients, high expression of CXCR4 correlates with poor survival and lower levels of relapse free survival